Protein name:
Ras-related GTP-binding protein A (Rag A;RagA) ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Can occur as a homodimer, or form a heterodimer with RRAGC or RRAGD in a sequence-independent manner. Binds GTP. The GTP-bound form of RRAGA interacts with NOL8.
Function:
Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.
Subcellular Location:
Cytoplasm
Nucleus
Lysosome
Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state.
Protein Attributes:
50:
MPNTAMKKKV | LLMGKSGSGK | TSMRSIIFAN | YIARDTRRLG | ATIDVEHSHV |
100:
RFLGNLVLNL | WDCGGQDTFM | ENYFTSQRDN | IFRNVEVLIY | VFDVESRELE |
150:
KDMHYYQSCL | EAILQNSPDA | KIFCLVHKMD | LVQEDQRDLI | FKEREEDLRR |
200:
LSRPLECACF | RTSIWDETLY | KAWSSIVYQL | IPNVQQLEMN | LRNFAQIIEA |
250:
DEVLLFERAT | FLVISHYQCK | EQRDVHRFEK | ISNIIKQFKL | SCSKLAASFQ |
300:
SMEVRNSNFA | AFIDIFTSNT | YVMVVMSDPS | IPSAATLINI | RNARKHFEKL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Bovine
Rat
ELISA Kit for Bovine Rag A
ELISA Kit for Bovine Rag A
ELISA Kit for Bovine Rag A
ELISA Kit for Bovine Rag A
CLIA Kit for Bovine Rag A
CLIA Kit for Bovine Rag A
CLIA Kit for Bovine Rag A
CLIA Kit for Bovine Rag A
Polyclonal Antibody for Bovine Rag A
Polyclonal Antibody for Bovine Rag A
Polyclonal Antibody for Bovine Rag A
Polyclonal Antibody for Bovine Rag A
Monoclonal Antibody for Bovine Rag A
Monoclonal Antibody for Bovine Rag A
Monoclonal Antibody for Bovine Rag A
Monoclonal Antibody for Bovine Rag A
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Uterus .